Overview InformationComfrey is a plant.
Even though this plant contains poisonous chemicals this web page pyrrolizidine alkaloids PAsthe leaf, root, and root-like stem rhizome are used to make medicine.
The amount of PAs found in comfrey changes according to the time of https://casinos-win-list.site/1/1358.html and the age of the plant.
The roots have 10 times higher amounts of PAs than the leaves.
Comfrey is used as a tea for upsetulcers, heavy menstrual periods,bloody urine, persistentpainful breathing pleuritis,and.
It is also used as a gargle for and.
Comfrey is applied to the for ulcers, wounds, joint inflammation, swollen veins, and.
How does it work?
The chemicals in comfrey might have a healing effect and reduce inflammation when applied to the skin.
However, comfrey contains toxic chemicals that can be absorbed through the skin.
Applying a comfrey extract ointment to the affected area for 5 days seems to decrease lower or upper back pain.
Also applying a cream containing comfrey extract plus methyl nicotinate to the affected area for 5 days seems to decrease back pain when resting or moving.
Applying www comfree com comfrey extract ointment to the affected area for 3 weeks or applying a specific cream containing comfrey extract, tannic acid, Aloe vera gel, eucalyptus oil, and frankincense oil to the affected are for 6-12 weeks seems to decrease pain in people with knee osteoarthritis.
Early research shows that applying comfrey ointment to the affected area for up to 2 weeks improves mobility, decreases pain, and reduces tenderness and swelling of sprains.
The effect of comfrey ointment in relieving pain and reducing swelling seems to be comparable to the effects of diclofenac gel.
Early research shows that applying comfrey directly to the skin for 2 weeks might decrease www comfree com and tenderness of bruises.
More evidence is needed to rate the effectiveness of comfrey for these uses.
Absorption of these chemicals increases if the skin is broken or if large amounts are applied.
Comfrey is LIKELY UNSAFE for anyone when taken by mouth.
It contains chemicals pyrrolizidine alkaloids, PAs that can cause liver damage, lung damage, and cancer.
The FDA has recommended removal of oral comfrey products from the market.
In addition to causing liver damage and possibly cancer, the PAs in comfrey might also cause birth defects.
Even topical use is unwise, since the PAs can be absorbed through the skin.
Doing so might expose you to large amounts of the chemicals in comfrey that can cause liver damage and other serious health effects.
Liver disease: There is a concern that comfrey might make liver disease worse.
Taking comfrey along with medication that might also harm the liver can increase the risk of liver damage.
Do not take comfrey if you are taking a medication that can harm the liver.
Some medications that can harm the liver include acetaminophen Tylenol and othersamiodarone Cordaronecarbamazepine Tegretolisoniazid INHmethotrexate Rheumatrexmethyldopa Aldometfluconazole Diflucanitraconazole Sporanoxerythromycin Erythrocin, Ilosone, othersphenytoin Dilantinlovastatin Mevacorpravastatin Pravacholsimvastatin Zocorand many others.
Some chemicals that form when the liver breaks down comfrey can be harmful.
Medications that cause www comfree com liver to break down comfrey might enhance the toxic effects of chemicals contained in comfrey.
Some of these medicines include carbamazepine Tegretolphenobarbital, phenytoin Dilantinrifampin, rifabutin Mycobutinand others.
About 4 grams of another cream containing 35% comfrey plus 1.
Randomized double-blind study: wound-healing effects of a Symphytum herb extract cream Symphytumxuplandicum Nyman in children.
Evaluation of the dietetic and therapeutic potential of a high molecular weight hydroxycinnamate-derived polymer from Symphytum asperum Lepech.
Regarding its article source, antilipoperoxidant, antiinflammatory, and cytotoxic properties.
Food Chem 2001;49 8 :3942-3946.
Some conservative strategies are effective when added to controlled mobilisation with external support after acute ankle sprain: a systematic review.
Analysis, separation, and bioassay of pyrrolizidine alkaloids from comfrey Symphytum officinale.
Comfrey extract ointment in comparison to diclofenac gel in the treatment of acute unilateral ankle sprains distortions.
Efficacy and safety of comfrey root extract ointment in the treatment of acute upper or lower back pain: results of a double-blind, randomised, placebo controlled, multicentre trial.
Efficacy of a comfrey root Symphyti offic.
Severe pulmonary hypertension possibly due to pyrrolizidine alkaloids in polyphytotherapy.
Carcinogenic activity of Symphytum officinale.
Cancer Inst 1978;61 3 :865-869.
Screening botanical extracts for quinoid metabolites.
Chem Res Toxicol 2001;14 11 :1546-1551.
Efficacy and tolerance of a comfrey root extract Extr.
Symphyti in the treatment of ankle distorsions: results of a multicenter, randomized, placebo-controlled, double-blind study.
Wirksamkeit und Vertraglichkeit von Beinwellextrakt Extr.
Topical symphytum herb concentrate cream against myalgia: a randomized controlled double-blind clinical study.
Adv Ther 2005;22 6 :681-692.
Efficacy and safety of topically applied Symphytum herb extract cream in the treatment of ankle distortion: results of a randomized controlled clinical double blind study.
Effects of Symphytum ointment on muscular symptoms and functional locomotor disturbances.
Ther 2000;17 4 :204-210.
Treatment with 4Jointz reduces knee pain over 12 weeks of treatment in patients with clinical knee osteoarthritis: a randomised controlled trial.
In general practice, 'always expect the unexpected'.
Physician 2008;37 4 :235-236.
Observational study of the use of Symphytum 5CH in the management of pain and swelling after dental implant surgery.
Mutagenicity of comfrey Symphytum Officinale in rat liver.
Br J Cancer 3-14-2005;92 5 :873-875.
Action of some proteic and carbohydrate components of Symphytum officinale upon normal and neoplastic cells.
Efficacy of a comfrey root extract ointment in comparison to a diclofenac gel in the treatment of ankle distortions: results of an observer-blind, randomized, multicenter study.
Comfrey: a clinical overview.
Res 2012;26 10 :1441-1448.
Evaluation of anti-inflammatory activity of some Swedish medicinal plants.
Inhibition of prostaglandin biosynthesis and PAF-induced exocytosis.
J Ethnopharmacol 1995;48 2 :61-76.
ECG for physicians: a potentially fatal case of mistaken identity.
Resuscitation 2008;76 3 :323-324.
Hepatic sinusoidal-obstruction syndrome: toxicity of pyrrolizidine alkaloids.
FDA Advises Dietary Supplement Manufacturers to Remove Comfrey Products From the Market.
The external use of comfrey: a practitioner survey.
Complement Ther Clin Pract.
Am J Med 1990;89:547-8.
Penetration of lycopsamine from a comfrey ointment through human epidermis.
Fortschr Med Orig 2002;120:1-9.
Metabolism, genotoxicity, and carcinogenicity of comfrey.
Journal Toxicol Environ Health B Crit Rev.
Combination of comfrey root extract plus methyl nicotinate in patients with conditions of acute upper or low back pain: a multicentre randomised controlled trial.
Medicinal plants in Europe containing pyrrolizidine www comfree com />Effect of a blend of comfrey root extract Symphytum officinale L.
Pyrrolizidine poisoning: a neglected area in human toxicology.
Ther Drug Monit 2001;23:698-708.
The efficacy and safety of comfrey.
Public Health Nutr 2000;3:501-8.
Human liver microsomal reduction of pyrrolizidine alkaloid N-oxides to form the corresponding carcinogenic parent alkaloid.
CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects.
This information may not fit your specific health circumstances.
Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD.
You should this web page speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.
This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version.
Information from this source is evidence-based and objective, and without commercial influence.
For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2018.
WebMD does not provide medical advice, diagnosis or treatment.
Making A Living Making Logos
The Web's Free 2019 ICD-10-CM/PCS Medical Coding Reference. ICD10Data.com is a free reference website designed for the fast lookup of all current American ICD-10-CM (diagnosis) and ICD-10-PCS (procedure) medical billing codes.
In my opinion you are not right. I am assured. Write to me in PM.
It at all does not approach me.
I think, that you are not right. I am assured. Let's discuss. Write to me in PM.
Remove everything, that a theme does not concern.
Instead of criticism advise the problem decision.
It is a pity, that now I can not express - I hurry up on job. But I will be released - I will necessarily write that I think on this question.
I consider, that you are not right. Write to me in PM.
This theme is simply matchless :), very much it is pleasant to me)))
In it something is. Now all became clear to me, Many thanks for the information.
In it something is also to me it seems it is excellent idea. Completely with you I will agree.
I thank for the information.